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Overview
Molecule is seeking a Pharmacist to build the formulation function from scratch, focusing on cognitive and performance compounds. Join a team at the intersection of biotech, blockchain, and AI. Molecule and BIO.xyz are building the foundation of Decentralized Science (DeSci) โ where biotech meets web3 to make scientific research community-owned, transparent, and faster to market. Molecule provides the infrastructure to turn intellectual property (IP) into programmable, on-chain assets through our IP-NFT framework and evolving protocol stack. This enables researchers, patients, and communities to fund and govern biotech projects in new, open ways. BIO.xyz is the coordination and economic layer of DeSci, powering BioDAOs through funding, governance, and ecosystem alignment. Together, we are creating a new model for scientific discovery โ one where breakthroughs are owned and advanced by the communities that believe in them.
What You'll Do
- โขDesign oral solid-dose formulations (capsules and tablets) from active properties up - excipient selection, diluents, binders, disintegrants, flow agents, and lubricants matched to each compound's solubility, stability, and dosing profile
- โขDesign sterile injectable formulations for our peptide pipeline - lyophile design, bulking agents, cryoprotectants, vial fill/finish at small scale, reconstitution protocols, and container-closure compatibility. Hands-on with EU GMP Annex 1 (sterile manufacturing) and applicable AMG/AMWHV requirements
- โขOwn encapsulation, blending, and aseptic processing end to end: powder characterization, blend uniformity, content uniformity, capsule fill weight control, scale-up from bench to production batches, and sterility assurance for the injectable side
- โขSolve hard actives. Bromantane and modafinil bring oral-side challenges - low aqueous solubility, poor flow, dose accuracy at small fill weights. Peptides like BPC-157, GLP-1 analogs, and GHK-Cu bring injectable-side challenges - stability across the lyophile/reconstitution cycle, copper-complex integrity, peptide aggregation. You develop the techniques that make all of them reproducible
- โขBuild and run the analytical backbone: dissolution testing, assay/potency, content and weight uniformity, sterility (Ph. Eur. 2.6.1), endotoxin (Ph. Eur. 2.6.14), and stability programs (ICH Q1A - accelerated and long-term) to establish shelf life
- โขWrite documentation that holds up: master formulation records, batch records, specifications, and SOPs. Define what "in spec" means and enforce it. Clean data trails or it didn't happen
- โขPartner with sourcing and QC on raw-material specs, incoming API characterization (identity, purity by HPLC, particle size), and supplier qualification. Build a qualified supplier network. Continuously improve - reduce variability, improve stability, lower cost-per-dose without compromising quality
What We Offer
- โขA senior IC seat building the formulation function from scratch at a company at the intersection of biotech, blockchain, and AI
- โขPre-approved capex - you spec the equipment: lyophilizer, capsule filler, balance suite, HPLC, dissolution apparatus, Class II BSC
- โขThe team you need, once you've proven the foundation
Who You Are
- โขDefends decisions with data. You'd rather run the test than guess. When asked why you chose X over Y, you have a data-grounded answer
- โขHigh bar on accuracy and sterility. It's people's health. Dose accuracy, reproducibility, and sterility are non-negotiable - especially on injectables
- โขExpert in the room alone. You work well as the sole expert on day one. No team around you for the first year, and that doesn't slow you down
- โขEngineers around complexity. You see the regulatory complexity of the compound classes we work with clearly, and you engineer around it rather than pretending it isn't there
Required
- โขApprobation als Apotheker/in (German pharmacist license), or an EU-recognized pharmacy qualification with a clear path to German licensure. Alternatively: a degree in pharmaceutics, pharmaceutical sciences, or industrial pharmacy (MSc/PhD) with equivalent hands-on formulation depth
- โข5+ years of hands-on formulation experience in pharma, nutraceutical, compounding, or contract manufacturing - covering oral solid dose and at least one of: sterile injectables, topicals
- โขDeep working knowledge of excipient functionality and compatibility, and of encapsulation/tableting unit operations
- โขPractical command of dissolution, content uniformity, and stability study design and interpretation
- โขExperience formulating poorly-soluble or low-dose actives
- โขWorking command of EU GMP (EudraLex Vol. 4), Annex 1 (sterile manufacturing), and the Apothekenbetriebsordnung (ApBetrO) or equivalent manufacturing-pharmacy framework
- โขRigor with documentation: batch records, specs, SOPs, and a clean data trail
Strongly Preferred
- โขSterile injectable / lyophilization experience - peptide formulations specifically
- โขBackground in a German Herstellungsapotheke, hospital pharmacy compounding unit, or EU-licensed contract manufacturer
- โขExperience formulating GLP-1 analogs (semaglutide, tirzepatide) or other peptide manufacturing under a quality-grade framework
- โขFamiliarity with cognitive/performance compounds, or with the broader peptide / longevity therapeutic landscape
- โขHands-on with HPLC, dissolution apparatus, particle sizing, Karl Fischer titration
- โขComfort owning scale-up from R&D batches to production
- โขWorking proficiency in German (regulatory and documentation context) and English (team working language)